Recombinant Rat PPAR-α protein (His tag)

Size: 100μg

Catalogue Numbers: PDER100044-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: PPAR-α

Target Synonym: PPAR alpha; PPARA; PPARalpha; PPAR-alpha; PPARMGC2452

UNIProt ID: P37230

Research Areas: Epigenetics and Nuclear Signaling; Neuroscience; Stem Cells; Cardiovascular; Metabolism

Target Species: Rat

Expression Host: E.coli

Fusion Tag: N-His

Accession: P37230

Background: Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha; NR1C1) is a member of the Nuclear Receptor superfamily. PPAR alpha exhibits the highest affinity with unsaturated fatty acids, and linolenic acids. PPAR alpha is expressed in brown fat, liver, kidney, heart, mucosa of the stomach and duodenum, retina, adrenal gland, skeletal muscle, pancreatic islets and smooth muscle cells. PPAR alpha plays important roles in lipid and glucose metabolism, and has been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three members have been identified and are called PPAR alpha, δ, and lambda. Retinoid X Receptor (RXR) is an obligate partner for PPAR.

Sequence: Ser 280-Leu 433

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 16.83 kDa

Observed MW: 18 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only